| Away | Home | Projection | Line | Over Win % | Under Win % | |
| Atlanta | @ | Miami | 6.21 | 4.5 | 72.2% | 27.8% |
| Cleveland | @ | Detroit | 4.17 | 4.5 | 45.5% | 54.5% |
| Cincinnati | @ | Philadelphia | 3.91 | 4.5 | 41.9% | 58.1% |
| Baltimore | @ | Tampa Bay | 4.32 | 4.0 | 54.4% | 45.6% |
| NY Mets | @ | Washington | 4.17 | 4.5 | 45.4% | 54.6% |
| Toronto | @ | NY Yankees | 4.25 | 4.5 | 46.6% | 53.4% |
| Milwaukee | @ | Chi Cubs | 3.79 | 3.5 | 54.0% | 46.0% |
| Boston | @ | Kansas City | 3.73 | 4.0 | 46.3% | 53.7% |
| Houston | @ | Minnesota | 5.79 | 4.5 | 67.1% | 32.9% |
| Pittsburgh | @ | St. Louis | 4.52 | 4.5 | 50.3% | 49.7% |
| Texas | @ | Colorado | 6.46 | 5.5 | 62.9% | 37.1% |
| Sacramento | @ | LA Angels | 4.46 | 5.0 | 42.7% | 57.3% |
| Chi Sox | @ | Seattle | 5.38 | 4.0 | 68.2% | 31.8% |
| LA Dodgers | @ | San Diego | 5.86 | 4.5 | 68.0% | 32.0% |
| SF Giants | @ | Arizona | 4.70 | 4.5 | 52.7% | 47.3% |