| Away | Home | Model Pick | Confidence | |
| Atlanta | @ | Miami | Miami +120 | Low |
| Cleveland | @ | Detroit | Cleveland -120 | Low |
| Cincinnati | @ | Philadelphia | Cincinnati +125 | Low |
| Baltimore | @ | Tampa Bay | Tampa Bay -124 | Low |
| NY Mets | @ | Washington | Washington +130 | Low |
| Toronto | @ | NY Yankees | NY Yankees -137 | Low |
| Milwaukee | @ | Chi Cubs | Chi Cubs -102 | Low |
| Boston | @ | Kansas City | Kansas City +112 | Low |
| Houston | @ | Minnesota | Minnesota -140 | Low |
| Pittsburgh | @ | St. Louis | St. Louis -108 | Low |
| Texas | @ | Colorado | Colorado +110 | Low |
| Sacramento | @ | LA Angels | Sacramento +115 | Low |
| Chi Sox | @ | Seattle | Seattle -152 | Low |
| LA Dodgers | @ | San Diego | San Diego +135 | Low |
| SF Giants | @ | Arizona | SF Giants +105 | Medium |