| * Probable Pitcher (not confirmed) | ||||||||
| **Expected to get bulk of innings | ||||||||
| Away | Pitcher | Win % | Fair Odds | Home | Pitcher | Win % | Fair Odds | |
| Atlanta | M Perez | 52.0% | -108 | @ | Miami | Garrett | 48.0% | +108 |
| Cleveland | Messick | 63.8% | -176 | @ | Detroit | Montero | 36.2% | +176 |
| Cincinnati | Burns | 47.5% | +111 | @ | Philadelphia | Luzardo | 52.5% | -111 |
| Baltimore | Bradish | 42.7% | +134 | @ | Tampa Bay | Jax | 57.3% | -134 |
| NY Mets | McLean | 52.9% | -112 | @ | Washington | Griffin | 47.1% | +112 |
| Toronto | Cease | 42.4% | +136 | @ | NY Yankees | Warren | 57.6% | -136 |
| Milwaukee | Misiorowski | 46.6% | +115 | @ | Chi Cubs | B Brown | 53.4% | -115 |
| Boston | R Suarez | 49.9% | +100 | @ | Kansas City | **Avila | 50.1% | -100 |
| Houston | McCullers | 38.4% | +160 | @ | Minnesota | Matthews | 61.6% | -160 |
| Pittsburgh | Keller | 42.9% | +133 | @ | St. Louis | Liberatore | 57.1% | -133 |
| Texas | Rocker | 52.0% | -108 | @ | Colorado | **T Gordon | 48.0% | +108 |
| Sacramento | J Lopez | 47.4% | +111 | @ | LA Angels | Detmers | 52.6% | -111 |
| Chi Sox | Kay | 36.5% | +174 | @ | Seattle | Br Miller | 63.5% | -174 |
| LA Dodgers | Sheehan | 50.4% | -102 | @ | San Diego | Canning | 49.6% | +102 |
| SF Giants | Roupp | 57.8% | -137 | @ | Arizona | Nelson | 42.2% | +137 |